cyclosporin v methotrexate

[bubblesgirl]

hi there, i'm a newbie but sadly not to P. I've had it for 24 years. I've been on mtx for quite a while but it didnt suit me so my derm has changed me over to cyclosporin. I start it today. Has anyone been on mtx and changed to C? Were the side effects easier to handle?
Hope to get to know you all over the coming weeks. 

[lilactime]

never tried meth . but started 8 weeks ago on cyclosporin . results so far are very good ! specially in the last week or so , not clear but significant improvement ! started on 200g a day , then after 6 weeks moved to 250g a day . no side effects apart from trembling lips and a cold which i may of caught anyway ? but everyone is different ? let us know how you get on

[arizona]

I dont think you will regret going on the ciclo, you may get some tiredness at first but that will go after a couple of months and it is usually faster working than metho. I had nearly 3 years of clear skin until it started to be not so effective and i started getting bad headaches

[bubblesgirl]

thanks for yr replies. Sounds very positive and i'm so glad its worked for you both. I guess i'm wary of starting it as its going to be a daily dose instead of weekly mtx and with mtx, the first few days each week were terrible.  I'm a mum so being stuck on the loo as well as being wiped out and being sick was very inconvenient!!

I'm prepared as much as i can be, i just hope it suits me better than mtx as i'm pretty much covered just now.

thanks again! 

[arizona]

thanks for yr replies. Sounds very positive and i'm so glad its worked for you both. I guess i'm wary of starting it as its going to be a daily dose instead of weekly mtx and with mtx, the first few days each week were terrible.  I'm a mum so being stuck on the loo as well as being wiped out and being sick was very inconvenient!!

I'm prepared as much as i can be, i just hope it suits me better than mtx as i'm pretty much covered just now.

thanks again! 

dont worry, you are unlikely to feel like that. Feeling pretty wiped out was the thing that got to me a bit but i was at the time trying to do a full time job plus a part time job and socializing too, once i stopped beating myself up about trying to keep up all those things it was much better and then after a couple of months i noticed i felt much more energised and even took up running and swimming as well 

[Stevie65]

My experience of Cyclo was very good and relatively quick acting, I was amazed with the results Whereas MTX can take longer to work.   As Arizona has stated this drug does come with side effects that can make you feel tired/wiped out nausia etc, this faded after a few weeks/month or two and didn't notice it much after that. Try to relax whenever you feel that way, I know it may be hard with a young family though. Make sure you have regular bloods and BP taken, the derm should advise you anyway.

Good luck

[bubblesgirl]

thanks stevie 

so far so good. I'm taking 150mg a day and took my first dose last night. Taking it at night so any side effects i can hopefully sleep off. But apart from feeling a bit icky this morning which wore off after my breakfast, i feel ok 

[bubblesgirl]

cyclosporin is so much better to cope with than mtx!!! 2nd day now and i'm feeling ok!!!! whoop whoop!

[lilactime]

ive been on it 9 weeks now and no side effects . have felt tired occasionally but this could be put down to work exercise ect . good results so far and im happy !

[bubblesgirl]

ive been on it 9 weeks now and no side effects . have felt tired occasionally but this could be put down to work exercise ect . good results so far and im happy !

thats brilliant!!! So happy for you!!!