LDN low dose naltrexone diary (with pics) by pieman...

[Pieman]

Day 44-55 LDN dose 3mg/3ml

no real change from last update really...i'm really willing ldn to work as with most treatments, us p people
embark upon, we want to see results and quick!!! i'm also a typical impatient bloke

I am seeing a small difference with some patches which are flattening in the middle with p spots on
the circumference of the patches, larger skin patches still scaling up at 3mg, although the process is slower to scale.
Scalp p has reared it's ugly head again...but not really that bad and is under control.
Facial P is nonexistant at the mo, not needed to use trimovate for over a week or so, even after agrivating my p
with the regular weekend beer binges

i now have some lush dream cream to moisturise with, so will see how that benefits my skin.

sofar done 4 weeks @ 1mg/1ml, 2 wks @ 2ml, 2 wks (nearly) @ 3ml.

from this monday will push up to 4mg/4ml daily and see how that goes.
pie

[Pieman]

day 56 - 59 ldn dose now 4mg/4ml:

Had a phone consultation with the doc at the EHC yesterday.
have agreed to up dose now to 4mg/4ml per day for the next 2 weeks.
Then up dose to to 4.5mg/4.5ml thereafter...the max permitted dosage for LDN is 5mg/5ml...
provided i can take this without side effect.

whilst chatting to the doc i asked from all the patients he has seen, what was their optimum dosage
which cleared them, which was 4-4.5mg interestingly enough and mainly between 3-4 month markers.

I myself have fastracked through the dosage and have now got to this doseage within the 2 month mark,
so will be looking seriously at LDN's mode of action for the next 2 months, hopefully to increase the limited
benefits i have achieved thus far.

Jeni...what proved to be the magic doseage for you...was it 3ml?

The dream cream is very easy to apply and keeps the p moisturised well, however will get through a 240g pot
within 4 days with my P and at £9.60 a pop, quite expensive.  I may need to negotiate a discount with lush
or enquire if they do a bigger pots, and order in bulk!!

skin pretty much the same as before, be looking at LDN giving my P a good kicking - and soon -  fingers X'd.
pie

[John Boy]

here too pieman fingers crossed for you

John & Sharon

[deedee5356]

Hi Mince (!) Pie

I think from the original thread, Jeni said 3.5ml was trigger point for her, but I guess gender/weight/severity of p must impact.  Hope the increased dosage makes some marked improvement for you.

Paul on to 2ml for just a couple of days now.  He's intending to "keep taking the medicine" for a good while and review perhaps end of January (3 month point for him).  Also taking vitamin D and omega 3 fish oil (just whatever it says on the tub!).

If we get around to doing a "review photoshoot", I'll try the dropbox thingy.  Just a technophobe really - frightened my pc will freeze, never to thaw!

By the way, are you puff or shortcrust?

Deedee

[Pieman]

shortcrust deedee ...i've just bought 6 boxes of mr kipling's from Morrison's..on special offer
buy 1 get 2 free ...quite a few of us pho members decided to add a xmas addition onto our display names
i thought mince-pie was appropriate!

you may be right about the gender/weight/severity of p....i may need to goto max with with my 17st 6'3" frame
i know also that vit D and omega 3 can help out too...I'll maybe look at that.

a "review photoshoot" eh? sounds very professional and glamorous although Paul may not agree with his p 
strike a pose and vogue
if you need any help on pic posting etc...give me a nod if you need to.

Anyway back to diary:
Day 60-67 LDN dose 4mg/4ml

been on 4mg for ten days now..and i think I'm at the turning point...having regular vivid dreams at the mo
certain small patches are flat and are not scaling(encouraging ) , bigger patches are though....but a lot slower scaling up.
Had a bad facial p breakout over the weekend coldsnap though...my forehead was snowing!!!
Have reigned the p there back in again.  I need to see a lot more from the LDN over the next 2 months before
decision to continue or not. am remaining positive!

will be looking at upping dose to 4.5mg/4.5ml from this coming Monday.
Also have a NHS hospital consultatant appt Friday to discuss how i am with the p at the moment.....

Have any other LDN'ers got updates on how they are doing? 

pie

[deedee5356]

6 boxes   I must need to get to the shops - have only a box of Tescos turkish delight thins and a tub of Jacobs cheese footballs in my Christmas Corner.  (That's behind the armchair that Paul and the daughter can't be bothered to pull out to get to the goodies!).

Deedee

[jeni001]

Hi Mince-pieman,
So, re your question - I ended up sticking on about the 3.5 doseage as it just seemed to work, although I think the key is more the timescale really rather than a high doseage.  By the time I got to 3.5 I had prob been on LDN for about 3/4 months and really only saw any noteable change after that amount of time then a lot more improvement by about 6/7 months - so all I can say is just have a lot of patience!!  I've actually come off LDN temporarily as am expecting baby no.2 and a bit wary of taking anything when pregnant although the essential health clinic have said it's fine.  I came off it about 6 weeks ago and it is slowly coming back, but v v slowly which is good - it's still only v small patches and no itching, so good to know that once it's done it's stuff it does last a little while    - hopefully for another 6/7 months until I get back on it!

Anyway, just keep going with it and really hope you see some good results in the next few months

[Pieman]

Just got back from NHS derm vist today and PASI score has reduced down to 21 compared to PASI 3 months back.

I am going to be prepped ready for Enbrel in march 2010 should LDN not prove itself, (funding approved)
so got my blood form to do and a enbrel patient info box to read up on!...
pie

[TrishR]

We you will certainly have given it a fair trial by then,   hopefully you won't need the Embrel eh! 

[deedee5356]

Congratulations Jeni! 

Deedee