I have had both ( typical junkie me )
out of the two ... the mtx worked the best , but the side effects for me we alot worse than aceterin
mtx made me sick for a few days, and washed out , but was good on P and joints
Aceterin just seems to dry you out .. lips nose and eyes, and makes you tired , and just keep p in stable state ...
but like everything we all react differently to each treatment :s but i would go for the mtx