I took part in a Pimecrolimus double blind trial nearly two years ago. Except for the poor sods on the placebo I believe most of us did very well. Personally I cannot enthuse enough about the oral drug (not the cream), my P nigh on totally cleared and the PA was remarkable in its remission. I could not remember having felt so well, physically and mentally. On ending the trial the bounce was most devastating as good health was taken for granted again, as one does for that is the natural state. I can't wait for Pimecrolimus to become available as there were no side effects other than a feeling of warmth in the skin. I was told that release is not imminent as further trials are ongoing.