Author Topic: E-monograph (Parts 1 and 2) about psoriasis pathogenesis  (Read 582 times)

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Offline Mikhail Inq

E-monograph (Parts 1 and 2) about psoriasis pathogenesis
« on: January 01, 2012, 09:43:24 PM »
I suggest to read these e-books (on English):
"Model of pathogenesis of psoriasis. Part 1. Systemic psoriatic process."
Edition e3.2 , MYPE, 2011. - 71 p. ISBN 978-5-905504-02-0
and
"Model of pathogenesis of psoriasis. Part 2.  Local processes.",
Edition e1.2,  MYPE, 2011. - 106 p. ISBN 978-5-905504-04-4

These e-books can be downloaded free:
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or here
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I will be grateful, if some of you find time to make comments and remarks
to these books.
Here and/or on Researchgate's topic
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PHO-topic about previous edition of Part 1: You are not allowed to view links. Register or Login

Offline Walterwalter

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Re: E-monograph (Parts 1 and 2) about psoriasis pathogenesis
« Reply #1 on: January 27, 2012, 08:41:11 PM »
Mikhail, are you coming close to recommendation of certain methods of psoriasis treatment? Meaning more effective methods, than usually and commonly accepted  ones? We hope that some day there will be kind of breakthrough, as it happened with ulcer treatment by killing helicobacter bacteria with special medications? You are not allowed to view links. Register or Login
With best wishes, and big hopes
                             Walter

Offline Mikhail Inq

Re: E-monograph (Parts 1 and 2) about psoriasis pathogenesis
« Reply #2 on: February 08, 2012, 08:30:47 PM »
I hope that my monograph will stimulate joint researches of the dermatologists, rheumatologists, gastroenterologists and microbiologists and approximate complete solution of the riddle of psoriatic disease.
In the future, treatment of psoriatic disease will be directed not to cosmetic and-or anti-inflammatory correction of local manifestations, rather elimination and-or decrease of action of original causes, i.e. in most cases, to the treatment of intestine dysfunctions:
I.e. Hyperpermeability of intestinal walls (subprocess SP1)
and
Growth of populations of Gram+ psoriagenic PsB and Gram(-) TLR4-active bacteria on small intestine mucosa (subprocess SP2).
The efficiency of such treatment will depend on the patient, his/her desire and possibility to control the way of life and diet.
As consequence, remission will be prolonged (or life-long! :)), probably supported by regular or periodic intake of medicines (bacteriophages, pre - and probiotics).

Now the further researches of psoriatics are necessary
1) small intestine microflora and ways of its correction
2) small intestine permeability and ways of its correction
3) Definition and studying of:
   - Fractionations of blood phagocytes (monocytes Mo and dendritic cells DC).
   - Properties of tolerized fractions and both subfractions Mo-R and DC-R. 

Let's hope that for this purpose will be available both groups of researchers and financing.

Offline Mikhail Inq

Re: E-monograph (Parts 1 and 2) about psoriasis pathogenesis
« Reply #3 on: May 09, 2012, 05:51:08 PM »
In the end of June in Stockholm
World conference on psoriasis and psoriatic arthritis will take place.
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Two demands for carrying out of reports have been made.
For today one report is accepted:
Small intestines microflora at psoriasis. Its possible role in pathogenesis.
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To present this report (in a poster form) it is necessary to me.
When the poster will be ready - it will be published near to theses...
I hope that the report will attract interest of participants of conference.
 ................
I would like to ask you to look at the presentation project to other report (which destiny while is unknown):
Psoriasis as reaction of skin to systemic psoriatic process SPP. Y-model of pathogenesis.
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I will be grateful for any questions and remarks, well and certainly for the well-founded criticism.