For those of you that use curcumin...

[stewart_h]

Not sure if this is of interest but Doctors Best are usually a very good brand, they claim to have improved the absorption rate of curcumin..

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[Vladex]

I buy curcumin as almost all of my supplements at purebulk.com
Why? Because they sell pure powder in bulk forms which I can use however I want and their prices are better for that.

[jjoblogs1]

 
anuvver article
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Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions.
Cheng AL, Hsu CH, Lin JK, Hsu MM, Ho YF, Shen TS, Ko JY, Lin JT, Lin BR, Ming-Shiang W, Yu HS, Jee SH, Chen GS, Chen TM, Chen CA, Lai MK, Pu YS, Pan MH, Wang YJ, Tsai CC, Hsieh CY.
Source
Department of Internal Medicine, National Taiwan University College of Medicine, Taipei. You are not allowed to view links. Register or Login

Abstract
Curcumin (diferuloylmethane), a yellow substance from the root of the plant Curcuma longa Linn., has been demonstrated to inhibit carcinogenesis of murine skin, stomach, intestine and liver. However, the toxicology, pharmacokinetics and biologically effective dose of curcumin in humans have not been reported. This prospective phase-I study evaluated these issues of curcumin in patients with one of the following five high-risk conditions: 1) recently resected urinary bladder cancer; 2) arsenic Bowen's disease of the skin; 3) uterine cervical intraepithelial neoplasm (CIN); 4) oral leucoplakia; and 5) intestinal metaplasia of the stomach. Curcumin was taken orally for 3 months. Biopsy of the lesion sites was done immediately before and 3 months after starting curcumin treament. The starting dose was 500 mg/day. If no toxicity > or = grade II was noted in at least 3 successive patients, the dose was then escalated to another level in the order of 1,000, 2,000, 4,000, 8,000, and 12,000 mg/day. The concentration of curcumin in serum and urine was determined by high pressure liquid chromatography (HPLC). A total of 25 patients were enrolled in this study. There was no treatment-related toxicity up to 8,000 mg/day. Beyond 8,000 mg/day, the bulky volume of the drug was unacceptable to the patients. The serum concentration of curcumin usually peaked at 1 to 2 hours after oral intake of crucumin and gradually declined within 12 hours. The average peak serum concentrations after taking 4,000 mg, 6,000 mg and 8,000 mg of curcumin were 0.51 +/- 0.11 microM, 0.63 +/- 0.06 microM and 1.77 +/- 1.87 microM, respectively. Urinary excretion of curcumin was undetectable. One of 4 patients with CIN and 1 of 7 patients with oral leucoplakia proceeded to develop frank malignancies in spite of curcumin treatment. In contrast, histologic improvement of precancerous lesions was seen in 1 out of 2 patients with recently resected bladder cancer, 2 out of 7 patients of oral leucoplakia, 1 out of 6 patients of intestinal metaplasia of the stomach, I out of 4 patients with CIN and 2 out of 6 patients with Bowen's disease. In conclusion, this study demonstrated that curcumin is not toxic to humans up to 8,000 mg/day when taken by mouth for 3 months. Our results also suggest a biologic effect of curcumin in the chemoprevention of cancer.

PMID: 11712783 [PubMed - indexed for MEDLINE]

[Lazza]

That's good to know.  I've seen on this forum where folks were taking as much as 3,000 mg per day, which I thought was an awful lot.  Yet I don't think I will ever take anywhere near that amount of curcumin.  Too darn expensive!


_Lazza

[jjoblogs1]

That's good to know.  I've seen on this forum where folks were taking as much as 3,000 mg per day, which I thought was an awful lot.  Yet I don't think I will ever take anywhere near that amount of curcumin.  Too darn expensive!


_Lazza

 
yes indeed,although its only about 4%? of turmeric,it dose costa bit,

the sooner they sort out the nano curcumin,mind that would be even more so...spose..

[LittlePinkPuss]

I have been using an American brand from a company called Thorne Research

They have ten different curcumin products, depending on what you need it for ~ the information on their website is very through and comprehensive in regards to this.

I am using Meriva-SR, as prescribed by my naturopath for bowel inflammation.

I take 2 tablets a day and each tablet is 250mg

I have found this to be an exceptionally excellent and good quality brand. It works well.

[Vladex]

I have 100 grams of curcumin, what food can be spiced with it?
I find that color of curcumin is really strong and hard to get rid of , even wash of but I am still intrigued by many health effects of it. The taste is very familiar but not that great now and maybe it takes time to grow on you.
Has anyone found any cheaper places that sell it ?
Purebulk is almost 400$ for 1KG but it goes down if you buy much more of it like 25KG for 5k

[LittlePinkPuss]

I have 100 grams of curcumin, what food can be spiced with it?

Goes fantastically in Indian curries - either meat or vegetable based.

Curry powder is basically a mix of curcumin, fenugreek and coriander. But you can add plain curcumin to curries or make a nice curry sauce to go with rice.

Cook the powder off quickly first in an oiled frying pan, to release the aromas.

I also juice turmeric root and add it to my main juices.

[Vladex]

I have curry but I also have curcumin as well. For now I just put it in yogourt as I heard it goes with the fatty food