Author Topic: Psoriacalm: 78%+ improvement in trials +30% discount for PHO members  (Read 34226 times)

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Offline stewart_h

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Salsera and I have been working on achieving a 30% discount for PHO memebrs with this new product that has been clinically trialled in France. It has had remarkable results and is a simple supplement capsule (you take 4 x twice a day) researched by a french dermatologist and clinically trialled on 108 patients (with double blind studies to come shortly). We have both started to take it. It isn't an overnight cure but the results seem to suggest that it is a solution if you stick with it for the 6 months it takes. It appears that those who conitnued the product after trial additonally went on to clear their psoriasis (average duration 4- 8 months).

Psoriasis treatment of Psoriasis by Marine Lecithin
by Doctor Paul Dupont, dermatologist.

 
The present study aims to evidence for the first time the benefit of marine lecithin in psoriasis. The study initially included 63 patients , and increased to 108   patients, who presented every known type of Psoriasis, with lesions evolving on average for a minimum of 10 years up to 20 to 30 years.

Each patient has taken 400mg of Marine Lecithin per day for a 6 month period. Concurrently, all other treatments were stopped. The results are evaluated on the PASI criteria of improvement and by photos. Results: on average the PASI50 (50% of improvement) is reached after 3 months and the PASI70 (average 78% improvement) is reached and exceeded at 6 months.

Patients: 108  psoriatic patients. All types of psoriasis (see below)  proving difficult to maintain with classic treatment. With an average age: 50 years old, (ranging from 18 to 82 years old) and an average duration of Psoriasis of 12 years with a third of life spent suffering this pathology and the necessary treatment.

Type of Psoriasis
   40 Plaque Psoriasis
   7 Flexural/Inversed Psoriasis
   14 Guttate Psoriasis
   2 psoriasis erythrodermic
   28 scalp psoriasis
   6 Palmo Plantar Psoriasis

Evaluation according to 3 criteria
   PASI score
   Patient's opinion
   Photo comparison

The Patients are seen again after 3 and 6 months of treatment.
The PASI score evaluates the extent of the lesions, their infiltration, scales and inflammation. Before treatment the average PASI score is 14,4, going from 0.6 to 54 After 6 months the average PASI score is at 2.4 which is equivalent to 78% of improvement. This score goes above the PASI 70.
« Last Edit: February 19, 2007, 12:17:00 PM by stewart_h »

Offline stewart_h

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Re: Psoriacalm: 78%+ improvement in psoriasis. 30% discount for PHO members
« Reply #1 on: February 19, 2007, 11:51:58 AM »
To order:

We have secured a 30% discount (+ free delivery on the 6 month order) for all PHO members. It takes 6 months for the psoriacalm to work so we have kept it, for the sake of ease, down to two options:

o   3 month supply @ 30% discount =  112 Euro + delivery charge
(estimate: £75.50 + delivery for the UK c£10)
o   6 month supply @ 30% discount =  224 Euro + free delivery
(Estimate: £151.50 + free delivery = equivalent of £25 a month)

To order please email us: You are not allowed to view links. Register or Login and we will send you the full trial details, the 30% discount password and details on how to order.

How to take:
4 capsules in the morning and 4 in the evening.
Once clear, reduce the dose to 3 capsules in the morning and evening for one month, then 2 then 1.
Many stay on a low mainteance dose of 1 capsule a day after that.

Discovery of marine lecithin's action (shortened story)
By Dr Paul Dupond, Dermatologist


For several years, trials to treat Psoriasis with Omega 3 have been carried out with mixed and seldom significant results. During the 80's, I myself had attempted to recommend salmon oil to my patients but without too much success.  Yet the benefits of omega for skin are well documented, so it interested me as to why the Psoriasis sufferer was not showing improvement. I pursued my research and came upon a potential missing link: an oil rich in marine based lecithin aswell as omega fatty acids.  
 
Marine based lecithin works alongside omega fatty acids by changing them into a more soluble form. Marine lecithin contains ‘phospholipids’ which could be compared to a sort of "energy pump” for the omega, helping it absorb into the body.  This molecule is bipolar, producing an exchange between water and oils whilst also bringing choline, serine and other molecules useful to calming and feeding the nervous system. The important fact here is that these energetic lipids can easily integrate into the membranes of our bodies cells. And, in such a way that the body is able to draw energy from it without having to expend energy to synthesize them.  

Added to this is that another characteristic of marine lecithin is its wealth in phosphatidylcholine with DHA. DHA is a variety of phospholipide which is naturally found in the brain and the skin (the exact two organs perturbed in the psoriasis sufferer). It is important to note that other forms of lecithin, such as the popular soya based lecithin, do not carry DHA and as such are missing part of the necessary jigsaw puzzle.  

Through research and experimentation, it became my experience that we in fact can treat psoriasis simply by compensating what appears to be a disease due to the lack of lecithin in the sufferer’s body.  
 
The hypothesis on the action of lecithin
 
We suspect that the cause of psoriasis lies within the liver. Our liver contains various enzymes that allow the body to synthesize what it needs to run and regulate itself. My hypothesis is that the psoriatic patient’s liver has as a deficiency of the enzyme that synthesises lecithin. With this enzyme missing the body remains low in lecithin and without lecithin the body cannot fully process the essential omega fatty acids only found in food.  
 
Essential fatty acids are of two kinds: omega-3 and omega-6. The only omega which is really essential are those which the body cannot manufacture, which food must bring to us in sufficient quantity. For omega-3 to be manufactured we need alpha-linoleic acid (ALA). From ALA the body manufactures the famous omega 3 that can also be found in fish. ALA also gives us Eicosapentanoïc Acid (EPA) and Docosahexanoïc Acid (DHA).  In the same way, the only omega 6 really essential is Linoleic acid (Al). The other omega-6 fatty acids can be manufactured by the body from it (Al).
 
These fatty acids once manufactured by the body benefit the brain and skin. Yet, it is only when they are carried by the lecithin that they become really useful. If the enzyme that manufactures lecithin is defective, the liver cannot manufacture and process enough omega 3 anymore. The only solution is thus to reload the body of it’s depleted reserves of lecithin and omega until the liver can take up its role again.  

My hypothesis on the mechanism of psoriasis is that it is the lecithin which is the missing link. The Omega reserves in the body may in fact not necessarily be fully depleted, but, due to the shortage of naturally occurring lecithin, the liver is unable to absorb and carry them. This explains why, only lecithin with omega 3 of marine origin functions.  
 
To summarise let’s return to the analogy of the pump. Even if there is water in the well, (ie even if there remain reserves of omega 3 in the liver, fat reserve) they cannot be used it if the pump is defused. At time of stress and illness, there is over consumption of lecithin. And once the lecithin is depleted the pump ceases functioning. It is only possible to correct the problem then by filling the pump: by bringing to the body a surplus of lecithin ready to be used by the body. And the best form of lecithin would be one naturally rich in omega 3 with DHA.  
  
In short, the over consumption of lecithin, whether due to stress, infection, trauma is each time the triggering factor. The hereditary deficiency of the enzymes in question is simply a tendency.

« Last Edit: February 22, 2007, 06:17:38 PM by stewart_h »

Offline stewart_h

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Re: Psoriacalm: 78%+ improvement in psoriasis. 30% discount for PHO members
« Reply #2 on: February 19, 2007, 11:52:21 AM »
How lecithin acts at the level of the nervous system.
 
The body manufactures nervous mediators, in particular acetylcholine of the parasympathetic system to alleviate the nerves and to retrieve calm and balances after the stresses. The return to balance results in a feeling of interior peace in opposition to the highs of worried concerns. When there is a deficiency in acetylcholine, it is very difficult to relax. The faulty nervous transmission causes a weakening in parasympathetic energy, (called in physiology the vagal brake). However the first symptom described by patients taking lecithin is precisely a kind of return to a state of calm interior.
   
The parasympathetic is the sedative side of the nervous system. Its function is to calm us back down and it does so automatically, without our conscious involvement. It acts however not just to calm us after the stresses but also to save vital energy. In essence, to avoid the overheating and over consumption of the engine.

When we are in distressing circumstances, it is the active side, the orthosympathetic one, which urgency produces adrenalin via the adrenals to boost us. But later after the traumatic circumstance has ceased, it is then necessary to alleviate and calm everything. Acetylcholine is used to do this. With the parasympathetic side it saves vital energy, decreases the speed of renewal of tissue, in particular of the skin. The skin replication rates increase when in fight and flight to give the body fast access to “wound healing”. But if acetylcholine, the substance necessary for the parasympathetic system to perform, is missing or depleted, the return to a state of calm is impossible. Then, the tension persists which causes a vicious circle as the body consumes even more of the already dangerously low reserves. We suggest that it may be in this continued state of tension that the skin remains “switched on” to the fight and flight overgrowth function.

It may not therefore surprise you that acetylcholine is precisely what is manufactured from lecithin. Lecithin deficiency thus causes stress and anxiety. 
 
The effect of the stress:
 
At the time of stress, if the liver does not release enough lecithin, it is the skin that reacts the most to the deficiency because it is the less regulated.  The skin starts to proliferate without maturing correctly. It is the characteristic of psoriasis. As in this case, it does not receive enough lecithin, and as the nervous system diverts the little which remains because of the stress, then the deficiency can last weeks, months and years. And it is a vicious circle because the stress also lasts him for the same reason: the deficiency. It is an exhausting race, as long as the lecithin reserve is not filled up.

On the level of the skin
 
Phospholipides in general and lecithin in particular regenerate the membranes of cells. where they are notably used to ensure its healing. It is interesting to observe how psoriasis is propagated gradually. Very often the plaques are circled by evolutionary lesions. We have the impression that the plaques attract to them the fat of the adjacent areas.
 
It is possible that lecithin, by ensuring the polarization of membrane and the passage of information from one cell to the other, supports a good co-operation between the fatty acids in the blood and those of the cells close by. In a state of deficiency, some lipids, coming from the blood, are rejected because they are badly solubilised, others on the contrary are consumed in the  neighbouring areas not yet affected by psoriasis which supports the extension and the persistence of the lesions. 
 
This would also explain why the application of corticoids creams blocks the psoriasis but ends up worsening it.  It works as if one was soaking a spot with a blotter while it continues to extend. As for those derived from vitamins D, a useful analogy would be as if one is sanding a tree trunk, it is never ending as more rough wood appears. 

« Last Edit: February 19, 2007, 11:54:22 AM by stewart_h »

Offline stewart_h

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Re: Psoriacalm: 78%+ improvement in psoriasis. 30% discount for PHO members
« Reply #3 on: February 19, 2007, 11:56:57 AM »
Discussion (editor: for the PHO members technically interested):

Results from our preliminary research suggests that Psoriacalm's  phospholipides which are rich in omega 3, instigate a regression of all types of psoriasis plaques. At this stage in regards to an active hypothesis we can only give suitable suggestions and leads to the relationship of psoriasis and phospholipides.

Inflamed psoriasis lesions are linked to several causes. First, a deficiency in Delta 6 desaturate, the enzyme responsible for bio-conversion of essential fatty acids into anti-inflammatory prostaglandins . This enzyme is insufficient in the Psoriatic epidermis [1] and therefore suggests that essential fatty acid goes unconverted causing pro-inflammation.
We must insist the fact that the fatty acid prostaglandin precursor inside the cells' membrane, are made into ester with the phospholipides.  Yet there are different types of phospholipids, and each one has very different functions.

It is there, that a second anomaly noticed in psoriasis, steps in: the increased activity of the phospholipase A2 (PLA2) . This enzyme acts directly on the menbrane's phospholipides. It frees the lines of pro-inflammatory ecosanoid . The PLA2 helps to synthesize the phosphorylcholine , the nervous precursor of acetylcholine . Inhibitors of the phospholipase A2 currently used to block the inflammation are the glucocorticoide  which work indirectly by the intermediary of the lipocortine. There are other peptides   inhibiting the phospholipase A2 called antiflammine.

The hypothesis that we are formulating is that the supplementation in some food phospholipids could unblock and regulate the synthesis of this necessary hormone for the nervous system in times of stress on the body. 

Offline Heidi Hi

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Re: Psoriacalm: 78%+ improvement in trials +30% discount for PHO members
« Reply #4 on: February 19, 2007, 12:44:13 PM »
Sounds great!!! I am on Bjmac regime at the moment so I cannot try this trial.
BUT I do hope it will work for you and Salsara, I shall be watching this thread with interest!!
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Until the bun in the oven is ready!

Offline lolarose

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Re: Psoriacalm: 78%+ improvement in trials +30% discount for PHO members
« Reply #5 on: February 19, 2007, 05:30:00 PM »


Thanks for sharing your discoveries with us It sounds very promising!

I am really interested in trying Psoriacalm, but unfortunately am on MTX at present. I have been on MTX for 4 months with no positive results so when I seem the derm in March I am hoping to come off and start UVB treatment. If so I will defo give this a go as I think in my case the alternative route is the way to go and must be a lot safer than my current treatment.


Paula

Offline Johnnnnny

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Re: Psoriacalm: 78%+ improvement in trials +30% discount for PHO members
« Reply #6 on: February 19, 2007, 07:33:56 PM »
a good read stewart, please keep us updated with any changes!  :)

Offline Rob_412

Re: Psoriacalm: 78%+ improvement in trials +30% discount for PHO members
« Reply #7 on: February 20, 2007, 03:15:52 PM »
wow, cheers for this stewart, it sounds well promising  ::)!!!! Please tell us if you find out any more ;)


Offline Scamble

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Re: Psoriacalm: 78%+ improvement in trials +30% discount for PHO members
« Reply #8 on: February 20, 2007, 04:45:58 PM »
Stewart,

Have emailed you for the info

Offline stewart_h

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Re: Psoriacalm: 78%+ improvement in trials +30% discount for PHO members
« Reply #9 on: February 20, 2007, 06:07:00 PM »
I have replied to all enquiries that were sent as of 6.00pm on or before 20th feb. Let usknow any questions on here.